Skip to main content
EURASIP Journal on Advances in Signal Processing
Download PDF
  • Research Article
  • Open access
  • Published:

Determining Patterns in Neural Activity for Reaching Movements Using Nonnegative Matrix Factorization

EURASIP Journal on Advances in Signal Processing volume 2005, Article number: 829802 (2005) Cite this article

Abstract

We propose the use of nonnegative matrix factorization (NMF) as a model-independent methodology to analyze neural activity. We demonstrate that, using this technique, it is possible to identify local spatiotemporal patterns of neural activity in the form of sparse basis vectors. In addition, the sparseness of these bases can help infer correlations between cortical firing patterns and behavior. We demonstrate the utility of this approach using neural recordings collected in a brain-machine interface (BMI) setting. The results indicate that, using the NMF analysis, it is possible to improve the performance of BMI models through appropriate pruning of inputs.

Author information

Authors and Affiliations

  1. Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL, 32611, USA

    Sung-Phil Kim & Jose C. Principe

  2. Motorola Inc., FL, USA

    Yadunandana N. Rao

  3. Department of Computer Science and Biomedical Engineering, Oregon Health & Science University, Beaverton, OR, 97006, USA

    Deniz Erdogmus

  4. Department of Pediatrics, Division of Neurology, University of Florida, Gainesville, FL, 32611, USA

    Justin C. Sanchez

  5. Department of Neurobiology, Center for Neuroengineering, Duke University, Durham, NC, 27710, USA

    Miguel A. L. Nicolelis

Authors
  1. Sung-Phil Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yadunandana N. Rao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Deniz Erdogmus
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Justin C. Sanchez
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Miguel A. L. Nicolelis
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jose C. Principe
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sung-Phil Kim.

Rights and permissions

Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Reprints and permissions

About this article

Cite this article

Kim, SP., Rao, Y.N., Erdogmus, D. et al. Determining Patterns in Neural Activity for Reaching Movements Using Nonnegative Matrix Factorization. EURASIP J. Adv. Signal Process. 2005, 829802 (2005). https://doi.org/10.1155/ASP.2005.3113

Download citation

  • Received:

  • Revised:

  • Published:

  • DOI: https://doi.org/10.1155/ASP.2005.3113

Keywords and phrases